Barrier Packaging Solutions

The Challenge

Reducing Moisture & Oxygen Impact on Formulations

Most APIs (up to 90%) used in pharmaceutical formulations are sensitive to moisture and/or oxygen and require passive or active protection.

 

With the ever-increasing complexity of the APIs and their drug formulations, innovative barrier packaging solutions are required for more and more pharmaceutical products in order for them to successfully pass stability tests.

Meeting the Challenge with LOG’s Barrier Packaging Solutions

LOG has developed a series of world-leading barrier packaging solutions to extend the shelf life and protect innovative and generic drugs from the exposure to moisture and/or oxygen. Made from up to six layers, LOG’s barrier packaging solutions are available for liquids and solids, and come in standard sizes from 15 to 1500ml and with neck finishes between SP20 and SP53.

 

The containers are compatible with LOG’s screw and CR closures and can be used on existing filling lines without the need for any modifications.

 

In addition to the standard barrier packaging portfolio, LOG also offers to partner with customers to develop tailor-made barrier packaging solutions.

LOG's Barrier Packaging Solutions are available in three product families

The OxyBlock™ multilayer product family offers protection for solid formulations that are sensitive to oxygen permeation.

Tests have shown that OxyBlock™ provides 100x better oxygen barrier performance as compared to standard HDPE containers.

Oxygen Transmission Rate (otr) - According to ASTM F-1307 23°C 50% RH

The MonoBlock™ product family offers protection for solid and liquid formulations that are sensitive to moisture permeation. Tests have shown that MonoBlock™ provides 4x better moisture barrier performance as compared to standard HDPE containers.

The MonoBlock™ family includes barrier bottles for liquids with a SP28 neck finish, as well as containers for solids with various neck openings.

Water Vapor Transmition Rate (WVTR) - According to ASTM F-1249, ASTM E-96 38°C 90% RH

The MultiBlock™ multilayer product family offers protection for formulations that are sensitive to oxygen as well as moisture permeation.

Tests have shown that MultiBlock™ provides 12x better moisture barrier performance and 100x better oxygen barrier performance as compared to standard HDPE containers.

Oxygen Transmition Rate (OTR) - According to ASTM F-1307 23°C 50% RH

Water Vapor Transmission Rate (WVTR) - According to ASTM F-1249, ASTM E-96 38°C 90% RH

LOG’s market-leading Barrier Packaging solutions:

  • Increase confidence to pass drug stability tests
  • Shorten drug formulation development time
  • Reduce the need for desiccants with the goal of eliminating them
  • Extend drug shelf life
  • Reduce head space and packaging size
  • Reduce total cost of ownership
  • Are successfully used and endorsed by global pharmaceutical companies
Do you have any questions about our standard packaging portfolio or customized solutions? Contact us